What is the 3-Hydroxyazetidine hydrochloride?

3-Hydroxyazetidine hydrochloride is white crystal, while it's Molecular Formula is C3H7NO . HCl. white crystal 3-Hydroxyazetidine hydrochloride is an building block used in a recent synthesis of a fluoroquinolone antibiotic and a useful intermediate in the synthesis of polypeptides.

What is the CAS number for 3-Hydroxyazetidine hydrochloride?

The CAS number of 3-Hydroxyazetidine hydrochloride is 18621-18-6.

What is 3-Hydroxyazetidine hydrochloride (18621-18-6) used for?

3-Hydroxyazetidine hydrochloride is a white crystalline compound that serves as a versatile intermediate in the synthesis of various pharmaceutical compounds, including polypeptides and fluoroquinolone antibiotics.InChI:InChI=1/C3H7NO.ClH/c5-3-1-4-2-3;/h3-5H,1-2H2;1H

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Product Name3-Hydroxyazetidine hydrochloride
CasNo. 18621-18-6
MFC₃H₇NO^.HCl
MW109.556
Purity
Appearancewhite crystal
Packing
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Product Details

CasNo： 18621-18-6

MF： C₃H₇NO^.HCl

Appearance： white crystal

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Molecular Formula:C3H7NO^.HCl
Molecular Weight:109.556
Appearance/Colour:white crystal
Vapor Pressure:0.464mmHg at 25°C
Melting Point:90-92 °C
Boiling Point:170.7 °C at 760 mmHg
Flash Point:120.4 °C
PSA：32.26000
LogP:0.08130

3-Hydroxyazetidine hydrochloride(Cas 18621-18-6) Usage

InChI:InChI=1/C3H7NO.ClH/c5-3-1-4-2-3;/h3-5H,1-2H2;1H

18621-18-6 Relevant articles

Development of an optimized process for the preparation of 1-benzylazetidin-3-ol: An industrially important intermediate for substituted azetidine

Krishna Reddy,Udaykiran,Chintamani,Mahesh Reddy,Kameswararao, Ch.,Madhusudhan

, p. 462 - 466 (2011)

A thoroughly optimized and robust proces...

Novel efficient synthesis of 1-azabicyclo[1.1.0]butane and its application to the synthesis of 1-(1,3-thiazolin-2-yl)azetidine-3-thiol useful for the pendant moiety of an oral 1β-methyicarbapenem antibiotic L- 084

Hayashi, Kazuhiko,Sato, Chisato,Hiki, Shinsuke,Kumagai, Toshio,Tamai, Satoshi,Abe, Takao,Nagao, Yoshimitsu

, p. 3761 - 3764 (1999)

1-Azabicyclo[1.1.0]butane 2 was successf...

Synthetic method of 3-hydroxyazetidine hydrochloride

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Paragraph 0081-0085; 0088-0090; 0093-0095, (2020/11/05)

The invention discloses a synthetic meth...

3-nitrile methylene azetidine-1-tert-butyl carbonate preparation method

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Page/Page column 8; 15-18, (2020/02/06)

The invention discloses a 3-nitrile meth...

A N - aryl heterocyclic butane de-aryl method (by machine translation)

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Paragraph 0022; 0024; 0025; 0027; 0028; 0030; 0031; 0033, (2019/05/28)

The invention discloses an aryl removing...

Method for preparing 3-hydroxyazetidine hydrochloride and tert-butyl 3-hydroxyazetidine-1-carboxylate

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Paragraph 0057; 0058; 0059; 0060; 0061; 0062; 0063, (2017/08/30)

The invention discloses a method for pre...

18621-18-6 Process route

: 90604-02-7
1-(diphenylmethyl)-3-azetidinol hydrochloride

: 18621-18-6
azetion-3-ol hydrochloride

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal; In ethanol; water; at 20 ℃; for 4h; under 2625.21 Torr;	100%
With palladium hydroxide on carbon; hydrogen; In ethanol; at 20 ℃; for 12h; under 3040.2 Torr; Inert atmosphere;	94%
With hydrogen; palladium hydroxide on carbon; In ethanol; at 20 ℃; for 12h; under 3040.2 Torr;	94%
With hydrogen; palladium(II) hydroxide/carbon; In methanol; for 48h; under 2844.39 Torr;	52%
With hydrogen; palladium hydroxide on carbon; In methanol; for 48h; under 2844.39 Torr;	52%
With hydrogenchloride; hydrogen; palladium on activated charcoal;
With hydrogen; palladium dihydroxide; In methanol; for 72h; under 2844.3 Torr;