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CasNo: 1378865-93-0
MF: C10H12F3N
PI3Kα has been identified as an ideal ta...
There are provided isotope-enriched comp...
Provided herein are processes and interm...

1,1,1-trifluoro-2-(4-methylpyridin-2-yl)propan-2-yl methanesulfonate


trimethylaluminum


4-methyl-2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine
| Conditions | Yield |
|---|---|
|
In hexane; cyclohexane; at 10 - 20 ℃; for 3.25h;
|
28% |
|
at 20 ℃;
|
|
|
In cyclohexane; for 16h;
|

C10H12NO2(1-)*Na(1+)


4-methyl-2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine
| Conditions | Yield |
|---|---|
|
With sulfur tetrafluoride; hydrogen fluoride;
|

2,4-lutidine

2-acetyl-4-methylpyridine

1,1,1-trifluoro-2-(4-methylpyridin-2-yl)propan-2-yl methanesulfonate

trimethylaluminum

alpelisib

C20H18F3N3O2S