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CasNo: 83883-26-5
MF: C16H20O5
The invention relates to a compound, a p...
Spiropyran-based materials (SPBMs) can g...
Liquid crystalline elastomers (LCEs) com...
The present invention relates to, an opt...

4-(6-hydroxyhexyloxy)benzoic acid


acrylic acid

![4-{[6-(acryloyloxy)hexyl]oxy}benzoic acid](/upload/2024/7/3efefe90-84bd-4984-9af8-a145875c1cd6.png)
4-{[6-(acryloyloxy)hexyl]oxy}benzoic acid
| Conditions | Yield |
|---|---|
|
With toluene-4-sulfonic acid; In benzene;
|
85% |
|
With toluene-4-sulfonic acid; In toluene; for 4h; Reflux;
|
80% |
|
With toluene-4-sulfonic acid; In toluene; for 4h; Reflux;
|
80% |
|
With toluene-4-sulfonic acid; hydroquinone; In benzene; for 5h; Dean-Stark; Inert atmosphere;
|
70% |
|
With toluene-4-sulfonic acid; hydroquinone; In benzene; for 20h; Heating;
|
67% |
|
With toluene-4-sulfonic acid; hydroquinone; In chloroform;
|
53% |
|
With toluene-4-sulfonic acid; hydroquinone; In benzene; for 12h; Reflux; Dean-Stark;
|
35.3% |
|
With toluene-4-sulfonic acid; hydroquinone; In benzene; Dean-Stark;
|
21.3% |
|
With toluene-4-sulfonic acid; hydroquinone; In chloroform; for 12h;
|
|
|
|
|
|
With toluene-4-sulfonic acid; hydroquinone; In tetrahydrofuran; hexane; toluene; for 6h; Heating / reflux;
|
|
|
With toluene-4-sulfonic acid; hydroquinone; In tetrahydrofuran; hexane, n-; toluene; for 6h; Heating / reflux;
|
|
|
With sulfuric acid;
|
|
|
With toluene-4-sulfonic acid; In toluene; for 4h; Dean-Stark; Reflux;
|
22g |

4-(6-hydroxyhexyloxy)benzoic acid


acryloyl chloride

![4-{[6-(acryloyloxy)hexyl]oxy}benzoic acid](/upload/2024/7/3efefe90-84bd-4984-9af8-a145875c1cd6.png)
4-{[6-(acryloyloxy)hexyl]oxy}benzoic acid
| Conditions | Yield |
|---|---|
|
In ISOPROPYLAMIDE; at 25 - 30 ℃; for 1.25h; Product distribution / selectivity;
|
100% |
|
In 1-methyl-pyrrolidin-2-one; toluene; at 25 - 40 ℃; Product distribution / selectivity;
|
95% |
|
With 10H-phenothiazine; In 1-methyl-pyrrolidin-2-one; at 25 - 30 ℃; for 3h; Product distribution / selectivity;
|
92% |
|
With N,N-dimethyl acetamide; In 1,4-dioxane; at 0 - 45 ℃; Inert atmosphere;
|
92% |
|
In N,N-dimethyl acetamide; at 15 - 20 ℃; for 2h;
|
91% |
|
In 1-methyl-pyrrolidin-2-one; acetonitrile; at 25 ℃; Product distribution / selectivity;
|
89% |
|
In 1-methyl-pyrrolidin-2-one; acetone; at 0 - 5 ℃; Product distribution / selectivity;
|
89.6% |
|
In tetramethylurea; at 25 - 40 ℃; Product distribution / selectivity;
|
86% |
|
With N,N-dimethyl-aniline; In tetrahydrofuran; for 12h;
|
85% |
|
With 10H-phenothiazine; In 1-methyl-pyrrolidin-2-one; at 10 - 15 ℃; for 6h; Product distribution / selectivity;
|
83.5% |
|
In 1-methyl-pyrrolidin-2-one; at -5 - 80 ℃; Product distribution / selectivity;
|
81.6% |
|
With N,N-dimethyl-aniline; In 1,4-dioxane; at 60 ℃; for 3h;
|
78% |
|
With N,N-dimethyl-aniline; In tetrahydrofuran; at 20 ℃; for 48.5h; Cooling with ice;
|
72% |
|
With triethylamine; In tetrahydrofuran; at 20 ℃;
|
64% |
|
In 1-methyl-pyrrolidin-2-one; acetonitrile; at 25 - 40 ℃; Product distribution / selectivity;
|
|
|
In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 25 - 40 ℃; Product distribution / selectivity;
|
|
|
In DMF (N,N-dimethyl-formamide); at 25 - 30 ℃; Product distribution / selectivity;
|
|
|
In acetonitrile; at 25 - 40 ℃; Product distribution / selectivity;
|
|
|
In dimethyl sulfoxide; at 25 - 40 ℃; Reactivity (does not react);
|
|
|
In tetrahydrofuran; at 25 - 40 ℃; Product distribution / selectivity;
|
|
|
In N-methylcaprolactam; at 25 - 40 ℃; Product distribution / selectivity;
|
|
|
In 1,4-dioxane; water; N,N-dimethyl-aniline; isopropyl alcohol;
|
|
|
With 2,6-di-tert-butyl-4-methyl-phenol; N,N-dimethyl-aniline; In tetrahydrofuran; for 4h; Heating / reflux;
|
|
|
With N,N-dimethyl-aniline;
|
|
|
With triethylamine; In tetrahydrofuran; at 0 ℃;
|
|
|
With 2,6-di-tert-butyl-4-methyl-phenol; N,N-dimethyl-aniline; In 1,4-dioxane; at 20 ℃; for 24h; Cooling with ice;
|
|
|
4-(6-hydroxyhexyloxy)benzoic acid; With triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;
acryloyl chloride; In tetrahydrofuran; at 0 - 20 ℃; for 25h;
|
1.66 g |

4-(6-hydroxyhexyloxy)benzoic acid

acrylic acid

1-bromo-6-hexanol

4-hydroxy-benzoic acid

acrylic acid 6-(4-chlorocarbonylphenoxy)hexyl ester

4-(6-acryloyloxy-hexyloxy)-benzoic acid 4-cyano-phenyl ester

(R)-2-(tetrahydropyran-2-yloxy)-2-phenylethyl 4-(6-acryloyloxyhexyloxy)benzoate

4-((ethoxymethoxy)carbonyl)phenyl 4-((6-(acryloyloxy)hexyl)oxy)benzoate